Comparison between Thermage and Rejuran

▲ Thermage FLX devices and Rejuran regenerative injections – two of South Korea’s most popular medical beauty treatments

✈️ When going to South Korea for cosmetic procedures for the first time, the two terms most often heard are “Thermage” and “Rejuran”. Many people struggle with this question before traveling: which of these two treatments should be done first? Or is it possible to have them both done at the same time? In today’s article, we will explain in the simplest terms the differences between these two treatments, their prices, effects, and the optimal order in which they should be performed.

🔥 Simply put, Thermage is a device-based treatment that “tightens loose skin”, while Rejuran is an injectable therapy that “restores skin health from the inner layers”. Since these two treatments address different issues and act at different levels, there is a general consensus in South Korea’s aesthetic medicine community: they are not opposing options, but rather a perfect combination that can be used together.

💡 If you are not very familiar with the medical beauty industry in South Korea, we recommend that you first read our previous article “The First Step for Beginners in South Korean Medical Beauty: Why Not Start with Basic Treatments Instead of Going Straight to Advanced Clinics? A Comprehensive Guide from Getting Started to Avoid Common Mistakes”. This article will help you gain a better understanding of the subject.

II. In-depth comparison of technical principles: Thermal tightening vs regenerative repair

🔬 Although both Thermage and Rejuran fall under the category of “anti-aging” treatments, their technical principles are entirely different. This is precisely why the two can be used in combination rather than being mutually exclusive.

1. Thermage — Polar radiofrequency technology that heats the skin layer by layer from the outside in 🔥

📡 The core technology of Thermage is Monopolar RF. Through the probe, high-frequency radio wave energy is delivered to the dermis and subcutaneous tissues at deeper levels of the skin, generating heat of approximately 55–65 degrees Celsius. This temperature causes Collagen fibers to contract immediately while simultaneously stimulating fibroblast cells to produce new Collagen, thereby achieving a dual effect of “immediate tightening + long-term collagen regeneration”.

⚡ The most significant improvements in the fifth-generation FLX Thermage include the “vibrating probe” and the “AccuREP™ automatic energy adjustment technology”, which significantly reduce the discomfort associated with the treatment. The treatment depth can reach up to 4.3 mm, covering the fibrous compartments from the dermis to the subcutaneous fat layer.

2. Rejuran – a PN polynucleotide that stimulates regeneration at the cellular level 🧬

🧪 The core ingredient of Rejuran is PN (Polynucleotide), a DNA fragment extracted from the reproductive cells of salmon. Once PN enters the skin, it does not simply act as a “filler”; rather, it functions as a “biological signal” – it activates the skin’s natural repair mechanisms, promotes the proliferation of fibroblasts, accelerates the formation of new microvessels, and regulates inflammatory responses. In short, Rejuran helps the skin become healthy on its own, rather than relying on external forces to tighten it.

📋 In South Korea, Rejuran is available in three main formulations: the Rejuran PN (I-POLY) box is designed for full-face rejuvenation, the Rejuran SWOMAN (S) box targets fine lines around the eyes, and the Rejuran HB box is used to treat acne scars and indentations. A complete treatment course usually requires 3–4 sessions, with each session spaced 3–4 weeks apart.

If you want to gain a deeper understanding of the principles and latest technologies behind Thermage, you may refer to “2026 South Korea Thermage Guide: Technical Evolution and Effect Analysis of the FLX Fifth Generation Thermage.”


Thermage FLX treatment probe

▲ Thermage FLX Probe – Utilizes monopolar radiofrequency technology, with a treatment depth of up to 4.3mm

III. Effect comparison: Whose results last longer? Whose improvements are more noticeable?

📊 This is probably the question that everyone is most interested in. For a clearer understanding, just look at the comparison table:

Comparative projects Thermage Rejuran
Primary effects Tightening and Lifting, Contour Enhancement Improvement in skin texture, increased glow, and enhanced elasticity
Time to take effect Reaches its peak within approximately 3 months Starting from 2 to 4 weeks, noticeable results can be seen after just 3 treatments.
Duration 12 to 18 months 6 to 12 months (annual maintenance is recommended)
Suitable for solving problems Loose skin, blurred jawline, and Nasolabial Fold Correction rough and dull skin, fine lines, Pores, redness
Frequency of treatment Once a year 3-4 sessions per treatment course

🎯 In a nutshell: Thermage targets “shrinking” skin, while Rejuran focuses on “aging” skin. If you notice that your face has become flatter or that your facial contours have faded, then Thermage is the right option for you; if you experience rougher skin, loss of glow, or the appearance of fine lines, then Rejuran is what you need.

📖 If you are also unsure about the differences between Thermage and other radiofrequency devices such as HIFU, we previously published a comprehensive comparison of South Korea’s Thermage and HIFU – covering effects, prices, and suitable candidates – which should help you make a more informed decision.


Schematic illustration of Rejuran’s skin regeneration effects

▲ Schematic illustration of how the PN polynucleotides in Rejuran act on the lower layers of the skin to promote the process of collagen regeneration

IV. Comparison of Recovery Periods and Postoperative Reactions: Which Option Is More Suitable for Those Who Are Sensitive to Pain?

😣 Many people are deterred from considering medical beauty treatments due to concerns about pain and long recovery periods. How do these two aspects perform in this regard?

1. Recovery period after Thermage treatment ⚡

💢 During the treatment process, there may be a brief sensation of intense heat, but the vibration probe of FLX Generation 5 has significantly reduced this discomfort. On the day of the procedure, the face may appear slightly red and swollen, but these effects usually subside within a few hours to a day. Most importantly, Thermage requires almost no recovery time in terms of social activities; you can apply makeup immediately after the treatment and return to work the next day without any issues.

⚠️ In very rare cases, some individuals may develop “grid-like red marks” due to the contact traces left by the probe; these marks usually disappear on their own within 1 to 3 days.

2. The recovery period after using Rejuran 💉

🩹 Rejuran is an injectable treatment that creates dozens of tiny needle holes on the skin. After the procedure, mild swelling resembling small papules may occur, which is a normal reaction indicating that the treatment is taking effect. Generally, it is recommended to avoid contact with water and makeup within 24 hours after the procedure; the swelling will subside within 1–3 days, and the needle holes will fully heal in 3–5 days. It is advisable to allow 3–5 days for recovery, and it is not recommended to attend any important events immediately after the treatment.

💡 Practical comparison: If you undergo Thermage treatment on Friday, you can go on a date as usual on Saturday; however, if you choose Rejuran on Friday, it is recommended to wait until Monday before meeting anyone again for better safety.


Thermage treatment process

▲ Treatment process of Thermage FLX – Almost no social recovery period required after the procedure

V. Comparison of actual prices in South Korea: Full-face Thermage vs Rejuran treatment

💰 Many people choose to go to South Korea for cosmetic procedures because the costs are lower than those in Taiwan. Here is the approximate price range for the South Korea market in 2026:

Treatment options Reference prices in South Korea Reference prices in Taiwan
Thermage FLX full-face treatment for 900 sessions ₩1,500,000 to 2,500,000 NT$60,000 to 100,000
Thermage FLX full-face treatment for 1,200 sessions ₩2,200,000 to ₩3,200,000 NT$80,000 to 130,000
Rejuran PN single use ₩300,000 to 600,000 NT$15,000 to 25,000
Rejuran PN 3-pack ₩800,000 to 1,500,000 NT$40,000 to 65,000

⚠️ The above prices are merely reference figures based on the market conditions in South Korea in 2026. Actual prices may vary depending on the clinic, the qualifications of the physicians, and any promotional offers available. Please consult the local clinics for accurate quotes. Information sources: South Korean medical beauty platforms Verym.net, Babitalk, and the official websites of BeautsGO (June 2026).

HUSHU Dermatology

HUSHU Dermatology

BeautsGO 認證

📍 Seoul, Gangnam District / Myeongdong

🚇 Just a 3-5-minute walk from Gangnam Station /
Myeongdong Station
🕐 Open Monday to Saturday, 10:00-19:00

✨ Thermage FLX · Rejuran full range · HIFU

💰 Project price reference
Recommended Projects Reference prices
Thermage FLX full-face treatment for 900 sessions Please visit BeautsGO for more information.
Rejuran PN for the entire face Please visit BeautsGO for more information.


📅 立即在 BeautsGO 預約檔期,查看完整項目報價

Environment of Thermage clinics in South Korea

▲ Thermage treatment environment at a professional Dermatology clinic in South Korea

VI. Ultimate Guide to Choice: Should you get Magi treatment first or Rejuran treatment first?

🎯 The most crucial question in this article has finally emerged: if both of you want to try these treatments, which one should you do first? The consensus in South Korea’s medical aesthetics community is to undergo Thermage first, and then Rejuran. Here is the complete reasoning behind this approach:

Why apply Thermage first? 🔑

🏗️ Thermage is a form of “structural treatment” – it uses radiofrequency energy to tighten the framework of your Collagen, thereby establishing a strong foundation for your skin. Imagine building a house: first, you need to construct a steel frame, and Thermage does exactly that for your face, helping to re-establish this essential framework.

Why apply Rejuran afterwards? 🧬

🌱 Rejuran represents a form of “high-quality treatment”: once the underlying framework is established, PN polynucleotides begin to repair the skin’s texture at the cellular level, making the skin more hydrated, glowing, and elastic. It’s like finishing the interior decoration after the steel structure has been built.

Your situation Recommended order
Loose skin + poor skin texture (the most common issues) ✅ First, use Thermage → 1–2 months later → then apply Rejuran
Only when the skin is relaxed and of decent quality. ✅ Just perform Thermage treatment alone.
The skin doesn’t become loose, but it does become dull and rough in texture. ✅ Just use Rejuran alone.
With a limited budget, I want to get it done all at once. ✅ You can first try treatments like Magi and Rejuran; you can come to South Korea again for these procedures later.

⏱️ Optimal interval: Wait for 1–2 months after undergoing Thermage treatment before receiving Rejuran. This period allows the collagen-enhancing effects of Thermage to fully take effect, and also enables the skin to complete its initial recovery process, resulting in better outcomes from the Rejuran treatment. It is not recommended to undergo both treatments on the same day, as the skin needs time to recover.

If you want to understand the detailed changes in the recovery process after Thermage treatment, you can refer to another article of ours that details the complete changes in the recovery periods at 1 day, 7 days, and 30 days after Thermage treatment. This will help you be better prepared for the entire process.


Schematic illustration of medical aesthetic injection treatments

▲ Rejuran is used in microneedling treatments, and a recovery period of 3 to 5 days is required after the treatment.

VII. Target Audience Analysis: Which product is right for your skin type?

Suitable for those who use Thermage 👩‍⚕️

✅ Aged 30+ and noticing that the face has started to sag; ✅ Blurred jawlines and excess fat around the mouth; ✅ Deepened Nasolabial Fold Correction; ✅ Seeking a treatment that lasts for more than a year; ✅ No need for a recovery period, wanting to return to normal daily activities the day after the procedure.

People who are suitable for using Rejuran 🧑‍⚕️

✅ Rough, dull skin with a loss of glow; ✅ Enlarged Pores and uneven skin texture; ✅ Visible fine lines, especially around the eyes and on the forehead; ✅ Skin that tends to flush easily and becomes sensitive; ✅ Looking for ways to improve skin health from the inside out, rather than just achieving temporary surface tightening effects.

People who are suitable for both options (the perfect combination) 🔥

✅ Aged 35 or above, experiencing both skin laxity and other skin-related issues; ✅ Have a budget to cover a full course of treatment at one time; ✅ Are willing to visit South Korea in two separate trips (or stay for more than 2 months in one visit); �✅ Seek comprehensive anti-aging results.

🏥 If you are looking for a clinic that is proficient in both Thermage and Rejuran treatments, we have previously conducted an in-depth review of DAN-A Dermatology in Myeongdong. We provide detailed information about the 14-year experience of the clinic’s director in performing Thermage treatments, as well as comprehensive price information. This clinic enjoys an excellent reputation within the Seoul medical aesthetics community.

DAN-A Dermatology

DAN-A Dermatology – Dana Clinic

BeautsGO 認證

📍 Seoul Myeongdong Business Dis
trict
🚇 3 minutes’ walk from Exit 6 of Myeo
ngdong Station
🕐 Open Monday to Saturday, 10:00–19:00

✨ 14-year-experienced director: Thermage FLX, Rejuran, HIFU

💰 Project price reference
Recommended Projects Reference prices
Thermage FLX full-face treatment for 900 sessions Please visit BeautsGO for more information.
Rejuran PN for the entire face Please visit BeautsGO for more information.


📅 立即在 BeautsGO 預約檔期,查看完整項目報價


South Korea’s Rejuran skin care programs

▲ The improvement in skin quality after the Rejuran treatment — a noticeable increase in glow and elasticity

VIII. Compilation of Real Discussions by Dcard/PPT Netizens

💬 We have compiled the popular discussions on Dcard and PTT regarding the topic of “Thermage vs Rejuran” to see what those who have actually undergone these treatments have to say:

🗣️ Netizen A (April 2026): “I went to South Korea and got Thermage FLX 900 + Rejuran PN; the treatments were spaced one and a half months apart. Let me share my conclusion first: this combination is truly unbeatable! Thermage took care of my jawline, while Rejuran PN made my whole face glow so brightly that my colleagues in Taiwan all asked me if I had changed my skincare products.” (Source: PTT Medical Beauty Section, April 2026)

🗣️ Netizen B (March 2026): “My budget was limited, so I only got Thermage treatment. To be honest, the results in terms of contour definition were not satisfactory, but my skin quality still benefits greatly from Rejuran. Next time I go to South Korea, I will definitely get more Rejuran treatments.” (Source: PTT Medical Beauty Section, March 2026)

🗣️ Netizen C (May 2026): “When I first went to South Korea, I only got Rejuran treatments because I was afraid that Hymage would be too painful. As it turned out, Rejuran is basically painless (local anesthetic is applied), and a week after the treatment, my skin quality improved significantly, but my facial contours didn’t change at all. Conclusion: Rejuran is truly a wonder product for skin care, but if you want defined facial features, Hymage is still the way to go.” (Source: Dcard Beauty Section, May 2026)

🗣️ Netizen D (February 2026): “The doctor recommended that I undergo Thermage and Rejuran on the same day, but after checking South Korea’s medical aesthetics forums, I found that most doctors actually advised doing them separately. In the end, I had Thermage first and then received Rejuran two months later – the results were incredible! I advise everyone not to go for the convenience of doing both procedures on the same day.” (Source: Dcard Medical Aesthetics Edition, February 2026)

📊 Based on the experiences of users from Dcard and PTT, over 80% of them recommend performing the treatments separately – first Thermage and then Rejuran. The satisfaction level of those who undergo both treatments on the same day is significantly lower.


Injection treatment programs at Dermatology clinics in South Korea

▲ The injection treatment environment in South Korea’s medical aesthetics clinics – professionalism, hygiene, and safety come first.

IX. Frequently Asked Questions

1. Can Thermage and Rejuran be done on the same day? 📅

⚠️ Most doctors in South Korea do not recommend performing these treatments on the same day. Thermage causes the skin to react with heat and develop mild swelling, while Rejuran requires the injection of PN through tiny needle holes. Performing both treatments simultaneously can increase the burden on the skin and may also affect their respective effectiveness. It is recommended to wait at least 4 to 8 weeks between them.

2. Is it okay to apply Rejuran first and then Thermage? 🔄

💡 Theoretically, it is possible, but this is not the optimal sequence. The PN components in Rejuran take several weeks to exert their regenerative effects. If Thermage treatment is performed during this period, the thermal energy generated by radiofrequency might interfere with the action of these components. Therefore, the industry consensus is still to “apply Thermage first and then use Rejuran”.

3. Does Thermage cause pain? Compared with Rejuran, which one is more painful? 😣

🔍 The types of pain experienced by these two treatments are different: Thermage causes an “instant burning sensation” – a brief heat feeling that lasts for about 1-2 seconds each time the probe comes into contact with the skin. The vibration function of FLX Generation 5 has significantly reduced this discomfort. Rejuran, on the other hand, produces a “multiple-point stinging sensation” because dozens of injection points need to be targeted across the entire face; however, since anesthesia is used, most people find this tolerable. Based on online reviews, the “instant pain” caused by Thermage is more intense than that of Rejuran, but it lasts for a shorter duration.

4. How much does it cost to undergo a full Thermage + Rejuran treatment? 💰

📊 Based on the market trends in South Korea in 2026, the cost of Thermage FLX full-face treatment is approximately ₩1.5–2.5 million, while the Rejuran PN 3-session package costs around ₩800,000–1.5 million. For a complete treatment package (including airfare and accommodation), it is recommended to budget around NT$70,000–100,000. The actual cost may vary depending on the clinic and any promotional offers; it is advisable to check the current prices through the BeautsGO platform.

5. How long will it take to see the results after the treatment? 📈

⏳ Thermage: Immediate tightening effects after treatment (about 20-30% efficacy), with peak results occurring after 3 months (when Collagen production is complete). Rejuran: Improvement in skin quality begins approximately 2-4 weeks after the first treatment, and the effects are most noticeable after completing 3 full treatment courses. When used in combination, the optimal results are usually achieved around the 3rd to 4th month.

6. Who is not suitable for undergoing Thermage or Rejuran treatments? 🚫

🛑 Contraindications for Thermage: Pregnancy, presence of a cardiac pacemaker, metal implants at the treatment site, or severe skin infections. Contraindications for Rejuran: Allergy to fish protein (since PN is derived from salmon), autoimmune diseases, or active infections at the treatment site. It is recommended to inform your doctor in detail about your medical history before the procedure.

7. What are the differences between what is done in South Korea and what is done in Taiwan? 🇰🇷🇹🇼

💸 The main differences lie in price and the variety of options available. The cost of Thermage treatments in South Korea is approximately 50-60% of that in Taiwan, while Rejuran treatments cost around 40-50% of the Taiwanese price. In addition, South Korea has a high density of clinics, fierce competition, and doctors with extensive experience, along with rapidly updated equipment. However, language barriers must be taken into consideration; it is recommended to choose clinics that offer Chinese translation services.


Schematic illustration of Thermage treatment results

▲ The effect of Collagen proliferation after Thermage treatment — Reconstructing the skin’s firm structure from the underlying layers

X. How to Make an Appointment

If you are interested in the services mentioned in this article, you can make an appointment in the following ways:

The recommended reservation method

Long-press to scan the QR code, or search for the WeChat ID to add. Please note in the remarks: “South Korea Medical Aesthetics Appointment”.

WeChat ID: F394666

📅
Book your appointment with BeautsGO.
One-click reservation, dedicated customer service

💬
LINE reservation
Add us as friends for online consultations.

📧
Book by email
Send an email, and a dedicated person will respond to you.

💡 預約小提示:

🔥 Medical Aesthetic Treatments

2026 South Korea Thermage Guide: How to Choose Between Ultrasound and Radiofrequency?

An in-depth analysis of the differences between Thermage FLX and HIFU, along with a side-by-side comparison of 4 Dermatology clinics in Gangnam District

🔥 Medical Aesthetic Treatments

Which is better, Thermage from South Korea or HIFU? A comprehensive comparison

A comprehensive comparison of price, effectiveness, and recovery time, along with a list of recommended clinics in Gangnam District.

🏥 Medical Aesthetics Clinic

DAN-A Dermatology in Myeongdong: Real experiences of Director Gemma Ji over 14 years

Operated personally by a senior director with 14 years of experience. The prices are transparent, and there is no pressure from sales pitches. All treatment records are available for your review.

🏥 Medical Aesthetics Clinic

Comprehensive Review of HUSHU Dermatology in 2026 | Complete Guide to Pricing, Services, and Appointments

With branches in both Gangnam and Myeongdong, offering services in Chinese, English, and Korean – view the complete price list and consultation process all in one place.

📘 Newcomer Guide

The First Lesson for Newcomers in South Korea’s Medical Aesthetics Industry: How to Avoid Common Mistakes

Why not avoid going straight to high-end clinics? A comprehensive guide for beginners, from making an appointment to post-operative care.

⏳ Recovery Guide

Complete records of the recovery periods 1 day, 7 days, and 30 days after Thermage treatment

From the swelling on the day of the surgery to the collagen proliferation one month later, a daily record of these changes is captured in real-time photographs.

📝 Article Summary

Thermage and Rejuran are not opposing options that you have to choose between; rather, they represent the “golden anti-aging combination” recognized in South Korea’s medical aesthetics industry. Thermage helps to tighten loose skin, while Rejuran works from within to restore the skin to a healthy, youthful state. If this is your first time undergoing medical aesthetics treatments in South Korea and your budget and time allow it, we recommend starting with Thermage and then proceeding with Rejuran, with an interval of 1–2 months between the two treatments. This approach will enable you to achieve the most comprehensive anti-aging results in 3–4 months. If you have any further questions about these treatment options, please do not hesitate to contact us through the reservation process above. We will recommend the most suitable clinic and doctor based on the condition of your skin.

By 優米